AlphaWhiteness: 100% Natural Whitening Active, an effective alternative to synthetic versions

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AlphaWhiteness: 100% Natural Whitening Active, an effective alternative to synthetic versions

Summary: Citroleo Group develops a 100% Natural Active for skin whitening, with superior effectiveness to the synthetic ones.

The outlook indicates that in 2021, the essence of beauty product innovations will be primarily the physical and mental well-being of the consumer, after all, researches point out that feeling good will be tantamount to looking more beautiful. This healthy appearance is becoming the desired consumption factor, so that associated with a healthier lifestyle, will be the consumption of products more aligned with the conservation of natural resources, sustainable sources and ethical positioning.

Hyperpigmentation of the skin may be associated with several factors, such as genetics, use of hormonal medicines, sun exposure, pregnancy, and others. The possible mechanisms of action for skin depigmentation involve the action of the actives in inflammatory processes, like post-inflammatory hyperpigmentation, inhibition of the enzyme tyrosinase, and consequently the decrease of melanin deposition in the keracinocytes. In addition, antioxidant action may be able to inhibit the oxidation steps necessary for the formation of melanin, causing a decrease in localized skin coloration. Other processes involve inhibition of melanin transfer from melanosomes to the outermost layers of the skin and the cell renewal, most commonly involved in the removal of excess melanin cells.

The hydroquinone, alpha-arbutin (an alpha-glycoside of hydroquinone) and acids including kojic acid and alpha-hydroxy acids (AHA) are being banned in some countries in Europe and Asia because of the deleterious effects of long-term use.

At the forefront of these studies, and in line with the main tendencies of consumption and behavior, Citróleo Group presents its whitening active, 100% natural and of vegetal origin, AlphaWhiteness. The product is composed of crude açaí oil, one of the greatest riches of Amazonian cosmetics, and the exclusive Citrue Bisabolol, the only true and active alpha-bisabolol 100% natural from the Candeia tree oil. AlphaWhiteness acts on the whitening and uniformity of the skin’s natural tone, as well as promoting pleasant sensory, deep hydration with dry touch.

Table 1. Comparison between the whitening effect of arbutin and alpha bisabolol


In the first colorimetric test, AlphaWhiteness promoted statistically significant whitening action in the armpits and in the groin of the participants after 30 days of use: 3% in the armpits and 6% in the groin. There were a total of 31 participants included in the study, aged between 18 to 65 years and skin phototypes from II to IV.

Figure 1. Participant V01, 39 years old, whose armpits color reduction was 40%.
The first photo shows the region before the application and the second image, the same area after 30 days of use of the product.



In the evaluation of cosmetic appreciability, the results speak for themselves: 97% of participants liked and would buy the product, 77% liked the texture of the product and 90% thought the product lightened the armpits. This result is according with the new perceptions of beauty: although non-natural whitening products exhibit seemingly faster results, they do not offer the benefit of experience and engagement that are afforded by the use of AlphaWhiteness. And this is clear from the results of this satisfaction survey.

In addition, 80% of the participants considered that the product cleared the groin, 93% considered that the skin became more uniform. With regard to AlphaWhiteness’s additional action, 83% of them considered the skin to be softer, 90% felt the skin more renewed and 93% felt the skin more hydrated after 30 days of use.

In tests performed on the face, a whitening of 2% bleaching was observed after 30 days of use. However, participants (33 men and women, aged from 30 to 60 and phototype II to IV) reported that they liked the product (88%), 64% thought the product had improved / cleared the skin spots and 73% felt that the product made the skin more uniform. These indices reinforce the trend that nowadays, in order to gain customers, companies need more than having a great product: they need to represent that “something more” and reflect a conscious message.

Figure 2. Example of the whitening effect of AlphaWhiteness, proportioner after 30 days of use (second photo), applied once a day.



Still, taking into account the effectiveness of AlphaWhiteness against other products on the market, a 2012 study showed that açai oil, with effective results in inhibiting the enzyme tyrosinase (IA50 – μg mL-1 – 50% inhibitory activity) had a longer duration of action compared to kojic acid – consider a standard for this activity, which makes it a promising product for skin whitening, since it reduces the need for constant reapplication of the product on the skin. See chart below, taken from the study:

Graph 1. Long-lasting effect of açaí oil on the inhibition of the enzyme tyrosinase, compared to kojic acid.


Meanwhile, in the same research cited above, about arbutin e alpha bisabolol, it is observed that although the alpha bisabolol concentration was even lower than the concentration of arbutin, it was sufficient to have a higher inhibitory rate of melanin production. It was also observed that the higher the concentration of alpha bisabolol the greater the proportion of the inhibitory rate of melanin production.

Table 2. Comparison between the inhibitory effect of arbutin melanin production and alpha bisabolol.



The active AlphaWhiteness is innovative because it can be applied to any skin type since the results of dermatological assessment of primary and accumulated dermal irritability and sensitization have shown that the AlphaWhiteness did not induce skin irritation and sensitization during the study. Therefore, the active supports the dermatologically tested claim. Applications can be made without restriction (night or day) unlike any other product on this line and this also includes sensitive skins. Thus, it presents itself as smooth, hydroquinone-free (market trend), with the best safety profile with prolonged use.

The following are some images of whitening effect on blemishes after 30 days of daily use of a base-product with the active AlphaWhiteness:

Visual improvement in skin texture, uniformity and wounds

Figure 3. Photos at the beginning of the tests.

Figure 4. Photos after 30 days of using AlphaWhiteness.



AlphaWhiteness has complete traceability, with a completely transparent and sustainable production chain. All efficacy tests performed were in-vivo, on volunteers, so that no animal testing was conducted. Thus the natural active brings in a single product a range of benefits provided by the synergy between two natural compounds, of 100% Brazilian sources and obtained in a sustainable and ethical way.


All this value can be aggregated into the final product; in May of this year, the global market research company, Euromonitor International, announced a breakdown of consumer trends: the seek for more natural, sustainable and ethical labels. In this briefing, it was observed that among the considered green-consumers, 6 of 10 of them prefer natural or botanical ingredients, even if this means a greater investment in the product. Of these 10, only one buyer reviews the financial aspect first.

Thus, the company offers the market an effective, 100% natural and sustainable alternative to whitening the skin. Moreover, due to the action potential of alpha bisabolol in inhibiting the production of melanin, AlphaWhiteness offers the prevention of the appearance of blemishes on the skin. Associated with the action of açai crude oil, this active guarantees a longer lasting effect than the non-natural ones, besides being safe, with no restrictions of use and no adverse effects reported.